Oxaprozin Pharmacology Physiotherapy

Oxaprozin and Rheumatoid Arthritis

In this article we will discuss Oxaprozin and Rheumatoid Arthritis

In this article, we will discuss Oxaprozin and Rheumatoid Arthritis. So, let’s get started.

Oxaprozin and Rheumatoid Arthritis

Rheumatoid arthritis: Oxaprozin was evaluated for managing the signs and symptoms of rheumatoid arthritis in placebo and active controlled clinical trials in a total of 646 patients. Oxaprozin was given in single or divided daily doses of 600 to 1800 mg/day and was found to be comparable to 2600 to 3900 mg/day of aspirin. At these doses there was a trend (over all trials) for oxaprozin to be more effective and cause fewer gastrointestinal side effects than aspirin.

Oxaprozin was given as a once-a-day dose of 1200 mg in most of the clinical trials, but larger doses (up to 26 mg/kg or 1800 mg/day) were used in selected patients. In some patients, Oxaprozin may be better tolerated in divided doses. Due to its long half-life, several days of Oxaprozin therapy were needed for the drug to reach its full effect.

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