In this article, we will discuss Oxaprozin and Rheumatoid Arthritis. So, let’s get started.
Oxaprozin and Rheumatoid Arthritis
Rheumatoid arthritis: Oxaprozin was evaluated for managing the signs and symptoms of rheumatoid arthritis in placebo and active controlled clinical trials in a total of 646 patients. Oxaprozin was given in single or divided daily doses of 600 to 1800 mg/day and was found to be comparable to 2600 to 3900 mg/day of aspirin. At these doses there was a trend (over all trials) for oxaprozin to be more effective and cause fewer gastrointestinal side effects than aspirin.
Oxaprozin was given as a once-a-day dose of 1200 mg in most of the clinical trials, but larger doses (up to 26 mg/kg or 1800 mg/day) were used in selected patients. In some patients, Oxaprozin may be better tolerated in divided doses. Due to its long half-life, several days of Oxaprozin therapy were needed for the drug to reach its full effect.