Dietary Factors and Cancer Risk Diet influences cancer risk in several ways. Some dietary factors raise risk for specific cancers. Others help lower risk. Overall dietary patterns matter more than single foods. Factors That Increase Risk Alcohol raises the risk of several cancers. These include cancers of the breast, colorectum, esophagus, liver, and head and […]
Novel Biomarkers for Predicting Response to Checkpoint Inhibitors Checkpoint inhibitors have transformed cancer treatment. These drugs block proteins such as PD-1, PD-L1 and CTLA-4. They allow the immune system to attack tumor cells. However, only a portion of patients respond well. Therefore, researchers seek reliable biomarkers to identify likely responders before treatment begins. Current biomarkers […]
Gastric Cancer Epidemiology Gastric cancer remains a major global health concern. It shows wide variation in occurrence across regions. In addition, incidence rates differ sharply between high-risk and low-risk populations. Therefore, understanding its distribution helps guide prevention and screening efforts. East Asia records the highest rates of gastric cancer. Countries such as Japan, South Korea, […]
New Drug Therapies for Multiple Myeloma Multiple myeloma treatment continues to advance rapidly. New therapies now target the disease more precisely and produce deeper responses. As a result, options for both newly diagnosed and relapsed patients have expanded significantly. First, bispecific antibodies have transformed care. These drugs engage T cells to attack myeloma cells. Teclistamab […]
Bispecific T-cell Engagers in Hematologic Malignancies Bispecific T-cell engagers redirect the immune system against blood cancers. These antibodies bind a tumor antigen on one arm and CD3 on T cells on the other arm. The linkage forces T cells to kill malignant cells. As a result, the approach bypasses the need for prior antigen presentation […]
Personalized Neoantigen mRNA Vaccines Targeting Hard to Treat Cancers Cancer vaccines train the immune system to recognize and attack tumor cells. Neoantigen vaccines focus on unique mutations found only in a patient’s cancer. mRNA technology delivers instructions for these neoantigens, so the body produces them and generates a targeted immune response. Researchers are testing these […]