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Physiotherapy

Role of Biomarkers Mesothelin, Fibulin-3 and Osteopontin in Mesothelioma Detection

Mesothelioma remains difficult to detect at an early stage. Doctors therefore explore blood and fluid-based biomarkers. Three proteins receive special attention. These are mesothelin, fibulin-3 and osteopontin. Each offers useful information for diagnosis and monitoring. Mesothelin appears in high amounts on mesothelioma cell surfaces. The body releases a soluble form into the blood. This form […]

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Physiotherapy

Emerging Liquid Biopsy Approaches for Monitoring Mesothelioma Progression

Liquid biopsy analyzes body fluids for cancer-related markers. Researchers apply this method to track mesothelioma progression. The approach avoids repeated invasive tissue biopsies. Therefore, it offers a safer option for patients. Mesothelioma often develops in the lining of the lungs or abdomen. Traditional monitoring relies on imaging and tissue samples. However, these methods have limitations. […]

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Physiotherapy

Sonrotoclax (Beqalzi) Approved as New Treatment for Relapsed Mantle Cell Lymphoma

Sonrotoclax (Beqalzi) Approved as New Treatment for Relapsed Mantle Cell Lymphoma Sonrotoclax is a next-generation BCL2 inhibitor. BeOne Medicines developed it. The drug carries the brand name Beqalzi. The FDA granted it accelerated approval in May 2026. Doctors can now use it for relapsed or refractory mantle cell lymphoma. Patients must have already received at […]

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Physiotherapy

SLNB vs Elective Neck Dissection in cN0 Oral Cancer

Clinically node-negative oral squamous cell carcinoma poses a treatment challenge. Occult metastases occur in a significant number of patients. Surgeons traditionally perform elective neck dissection to address this risk. Sentinel lymph node biopsy offers a less invasive alternative. It identifies the first draining lymph nodes. Surgeons then examine these nodes for cancer cells. A negative […]

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Physiotherapy

Mesothelioma Pathophysiology: How Asbestos Fibers Damage Cells

Mesothelioma Pathophysiology: How Asbestos Fibers Damage Cells Mesothelioma develops when asbestos fibers enter the body and disrupt normal cell function. These fibers are sharp, durable, and resistant to breakdown. Once inhaled or ingested, they lodge in the lining of the lungs, abdomen, or heart. Fiber Inhalation and Retention Asbestos fibers bypass natural defense mechanisms in […]

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Physiotherapy

Spatio-Temporal Analysis of Mesothelioma Incidence and Asbestos Exposure Using Cancer Registry Data

Researchers conduct a spatio-temporal analysis of mesothelioma incidence. They also examine asbestos exposure patterns. The study relies on statistical modeling of incidence rates. Cancer registry records and occupational history data provide the main sources. Scientists map cases across different regions and time periods. They identify clusters and changing trends. In addition, they link these patterns […]