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Physiotherapy

Role of Lung Microbiota in RA Pathogenesis and Interstitial Lung Disease Progression

Role of Lung Microbiota in RA Pathogenesis and Interstitial Lung Disease Progression Lung microbiota plays a significant role in rheumatoid arthritis (RA). These communities of microorganisms in the lungs influence disease development. Moreover, they contribute to complications like interstitial lung disease (ILD). Lung Microbiota and RA Pathogenesis Researchers observe changes in lung microbial balance among […]

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Physiotherapy

Gene Therapy Approaches for Osteoarthritis: Focus on IL-1Ra Delivery

Gene Therapy Approaches for Osteoarthritis: Focus on IL-1Ra Delivery Researchers actively explore gene therapy to treat osteoarthritis. This approach delivers therapeutic genes directly into joint tissues. One promising method involves IL-1Ra delivery. IL-1Ra blocks harmful inflammation caused by interleukin-1. As a result, it helps protect cartilage and reduce pain. How IL-1Ra Gene Therapy Works Scientists […]

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Physiotherapy

Patient-Reported Outcome Measures in Rheumatic Diseases: Development and Validation of Culturally Adapted Tools for Indian Populations

Patient-Reported Outcome Measures in Rheumatic Diseases: Development and Validation of Culturally Adapted Tools for Indian Populations Patient-reported outcome measures play a vital role in rheumatology. Doctors and researchers use PROMs to understand how patients experience their diseases. These tools capture pain levels, daily functioning, emotional well-being, and quality of life directly from patients. However, most […]

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Physiotherapy

Enthesitis and Functional Disability in Psoriatic Arthritis: Clinical Scoring Systems Validation in Indian Patients

Enthesitis and Functional Disability in Psoriatic Arthritis: Clinical Scoring Systems Validation in Indian Patients Psoriatic arthritis affects many patients in India. This condition causes inflammation where tendons and ligaments attach to bones, known as enthesitis. Moreover, it leads to significant functional disability. Doctors need reliable clinical scoring systems to assess these problems accurately. Researchers validate […]

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Physiotherapy

Axial Spondyloarthritis Diagnosis Delay in India: Factors Contributing to Late Presentation and Functional Impact

Axial Spondyloarthritis Diagnosis Delay in India: Factors Contributing to Late Presentation and Functional Impact Axial Spondyloarthritis (axSpA) is a chronic inflammatory disease. It mainly affects the spine and sacroiliac joints. However, many patients in India face long delays before receiving a correct diagnosis. Doctors often identify axSpA after 6 to 10 years of symptom onset. […]

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Physiotherapy

Analysis of Large Vessel Vasculitis and Imaging Biomarkers for Disease Monitoring

Analysis of Large Vessel Vasculitis and Imaging Biomarkers for Disease Monitoring Large vessel vasculitis (LVV) affects the aorta and its major branches. Doctors commonly diagnose two main types: Giant Cell Arteritis and Takayasu Arteritis. Early detection plays a crucial role in preventing serious complications. Furthermore, imaging techniques help doctors monitor disease activity effectively. They provide […]