In this article we will discuss about the Treatment of Multiple Myeloma. So let’s get started.
Treatment
Drug therapy for Multiple Myeloma include
Chemo drugs like Melphalan, Cyclophosphamide, Vincristine etc
Corticosteroids like Dexamethasone etc
Immunomodulating agents like Thalidomide,Lenlidomide etc
Proteasome Inhibitors like Bortezomib,Carfilzomib etc
Histone deacetylase inhibitors like Panobinostat.
Monoclonal antibodies like Daratumumab,Elotuzumab.
Medical management of primary induction therapy in patients with multiple myeloma National Comprehensive Cancer Network recommend following combinations of Proteasome Inhibitors,Immunomodulating agents or Chemotherapeutic drugs and Corticosteroids :-
Bortezomib/lenalidomide/dexamethasone
Bortezomib/cyclophosphamide/dexamethasone
Other drug combinations include
lenalidomide/dexamethasone
Carfilzomib/lenalidomide/dexamethasone
Panobinostat/bortezomib/dexamethasone
Elotuzumab/bortezomib/dexamethasone
Vincristine/doxorubicin/dexamethasone
Melphalan/prednisone with or without thalidomide or bortezomib
Dexamethasone/cyclophosphamide/etoposide/cisplatin
Dexamethasone/thalidomide/cisplatin/doxorubicin/cyclophosphamide/etoposide with or without bortezomib
Biphosphonates are used for associated bone diseases
Adjunct Therapy include
Surgical Intervention
Plasmapheresis
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