Amsacrine Anticancer Drugs Oncology Pharmacology Physiotherapy

Amsacrine (Oncology-6)

In this article we will discuss Amsacrine (Oncology-6)

In this article, we will discuss Amsacrine (Oncology-6). So, let’s get started.

About 97% of a dose of amsacrine is bound to protein bound in plasma in both
cancer patients and healthy volunteers. Studies of human plasma in vitro showed no change in protein binding across a concentration range of 1–100 μmol/L. The unbound fraction increased to 21.7%, however, when the pH was changed to 6.4 (Paxton et al.,1986). No studies of the metabolism of amsacrine in humans have been published.

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