In this article, we will discuss Amsacrine (Genetics and Related Effects). So, let’s get started.
General reviews on the mutagenicity of inhibitors of DNA topoisomerase II
enzymes, including amsacrine, have been published (Anderson & Berger, 1994;
Ferguson & Baguley, 1994, 1996; Baguley & Ferguson, 1998). Jackson et al. (1996)
collated a genetic activity profile for this drug.