Differential Diagnosis of Aplastic Anemia

In this article, we will discuss Differential Diagnosis of Aplastic Anemia. So, let’s get started.

Differential Diagnosis

Aplastic anemia should be differentiated from other conditions producing pancytopenia such as:

1. Subleukemic or aleukemic leukemia

2. Myelodysplastic syndrome

3. Hypersplenism (e.g. portal hypertension, infiltrative splenomegaly)

4. Bone marrow infiltration (carcinoma, myelofibrosis)

5. Megaloblastic anemia

6. Osteoporosis (marble bone disease)

7. Systemic lupus erythematosus

8. Paroxysmal nocturnal hemoglobinuria

9. Disseminated tuberculosis

10. Overwhelming infection

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