In this article we will discuss Anlotinib (Background-1). So, let’s get started.
Receptor tyrosine kinases (RTKs) are transmembrane glycoproteins that communicate with cellular growth factors and extracellular ligands. They play important roles in intracellular tyrosine phosphorylation and intracellular signaling. RTK activation mediates many vital physiological processes including cell proliferation, cell growth, cell migration, cell differentiation, and apoptosis. In addition, RTKs have been implicated in a variety of pathological conditions, including cancer, metabolic and autoimmune disorders, infectious diseases, and neurodegenerative disorders.