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Anticancer Drugs Medicine Octreotide Oncology Pharmacology Physiotherapy

Octreotide

In this article we will discuss Octreotide (Dosage Overview)

In this article, we will discuss Octreotide (Dosage Overview). So, let’s get started.

Indications

Octreotide LAR is a somatostatin analogue indicated for:
Treatment in patients who have responded to and tolerated Octreotide Injection subcutaneous injection for:
• Acromegaly
• Severe diarrhea/flushing episodes associated with metastatic carcinoid
tumors
• Profuse watery diarrhea associated with VIP-secreting tumors

Dosage

Patients Not Currently Receiving Octreotide Injection subcutaneously:
• Acromegaly: 50 mcg three times daily Octreotide Injection subcutaneously for two weeks followed by Octreotide LAR 20 mg
intragluteally every 4 weeks for 3 months.
• Carcinoid Tumors and VIPomas: Octreotide Injection subcutaneously 100-600 mcg/day in 2-4 divided doses for two weeks followed by Octreotide LAR 20 mg every 4 weeks for 2 months.

Patients Currently Receiving Octreotide Injection subcutaneously:
• Acromegaly: 20 mg every 4 weeks for 3 months.
• Carcinoid Tumors and VIPomas: 20 mg every 4 weeks for 2 months.

Renal Impairment, patients on dialysis: 10 mg every 4 weeks.
Hepatic Impairment, patients with cirrhosis: 10 mg every 4 weeks.

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