Anticancer Drugs Oncology Osimertinib Pharmacology Physiotherapy


In this article we will discuss Osimertinib (Dosage Overview)

In this article, we will discuss Osimertinib (Dosage Overview). So, let’s get started.


Osimertinib is indicated for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC), as detected by an FDA-approved
test, who have progressed on or after EGFR tyrosine kinase inhibitor (TKI) therapy.
This indication is approved under accelerated approval based on tumor response rate and duration of response.


Patient Selection
Confirm the presence of a T790M EGFR mutation in tumor specimens prior to initiation of treatment with Osimertinib.

Recommended Dosage Regimen
The recommended dose of Osimertinib is 80 mg tablet once a day until disease progression or unacceptable toxicity. Osimertinib can be taken with or without food. If a dose of Osimertinib is missed, do not make up the missed dose and take the next dose as scheduled.

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