In this article, we will discuss the Structure and Transmission of Coronavirus. So, let’s get started.
They are enveloped viruses with a positive-sense-single-stranded RNA genome and a nucleocapsid of helical symmetry. The genome size of coronaviruses ranges from approximately 27 to 34 kilobases. ‘Coronavirus’ the name is derived from latin word ‘corona’ which means crown or halo referring to the characteristic appearance of a crown around the virus particles when viewed under 2-D TEM (transmission electron microscopy).
Transmission (human to human) is primarily through close contacts via respiratory droplets generated by sneezing or coughing. The interaction of coronavirus spike protein with its complement host cell receptor is central in determining the tissue tropism, infectivity, and species range of the virus. SARS Coronavirus infects human cells by attaching to ACE2 (angiotensin converting enzyme) receptor.