Sampling the Parietal Pleura to Separate Biphasic from Pure Forms Malignant mesothelioma on the parietal surface is not one uniform tumour. Pathologists sort it into three main histologic types. Epithelioid, sarcomatoid, and biphasic patterns change diagnosis, behaviour, and treatment talk. The chest-wall lining does not invent a fourth family. It does decide how those three […]
Tag: Oncology
Li-Fraumeni Syndrome and Secondary Bone Sarcoma Li-Fraumeni syndrome is a rare inherited cancer predisposition. A germline TP53 mutation causes it in most families. The gene normally helps control DNA repair and cell death. When it fails, cancers arise at younger ages and in several organs. Classic tumors include soft-tissue sarcoma, osteosarcoma, premenopausal breast cancer, brain […]
In this article we will discuss Understanding Aneurysmal Bone Cyst (ABC): Causes, Symptoms, and Treatment
Mesothelioma remains difficult to detect at an early stage. Doctors therefore explore blood and fluid-based biomarkers. Three proteins receive special attention. These are mesothelin, fibulin-3 and osteopontin. Each offers useful information for diagnosis and monitoring. Mesothelin appears in high amounts on mesothelioma cell surfaces. The body releases a soluble form into the blood. This form […]
Liquid biopsy analyzes body fluids for cancer-related markers. Researchers apply this method to track mesothelioma progression. The approach avoids repeated invasive tissue biopsies. Therefore, it offers a safer option for patients. Mesothelioma often develops in the lining of the lungs or abdomen. Traditional monitoring relies on imaging and tissue samples. However, these methods have limitations. […]
Sonrotoclax (Beqalzi) Approved as New Treatment for Relapsed Mantle Cell Lymphoma Sonrotoclax is a next-generation BCL2 inhibitor. BeOne Medicines developed it. The drug carries the brand name Beqalzi. The FDA granted it accelerated approval in May 2026. Doctors can now use it for relapsed or refractory mantle cell lymphoma. Patients must have already received at […]