Definition of Dengue Hemorrhagic Fever

In this article, we will discuss the Definition of Dengue Hemorrhagic Fever. So, let’s get started.

Definition

Dengue hemorrhagic fever is characterized by all manifestations of classical dengue fever, thrombocytopenia, vascular instability, and increased permeability resulting in leakage of intravascular fluid to interstitial space (hemoconcentration) and local hemorrhage (positive tourniquet test, spontaneous petechiae, and/or purpura) or frank hemorrhage (epistaxis, gum bleeding, bleeding into GI tract, i.e. melena or hematochezia) have been described. The hemorrhage is inconstant and is thought to be a combined effect of vascular damage and thrombocytopenia.

As the plasma leakage increases, patient may become restless, irritable, and develops hypotension and shock (cold extremities) called dengue shock syndrome (DSS). In severe cases, frank shock is present with low pulse pressure (<20 mmHg), cyanosis, hepatomegaly, pleural effusion, and ascites. In some cases, severe ecchymosis and GI bleeding may be seen.

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What is Dengue Virus?

In this article we will discuss about “Dengue Virus” and also about its “mode of transmission” so, lets get started.

Virus

Group- Group(IV) +ve single stranded RNA virus

Family- Flaviviridae

Genus- Flavivirus

Species- Dengue Virus

Mode of Transmission

It is transmitted to humans through the bite of female Aedes mosquito primarily Aedes Aegypti and other less commonly causing species includes Aedes albopictus, Aedes polynesiensis, and Aedes scutellaris.

This is an endemic illness and occurs regularly in tropical and sub tropical regions around the world.

Incubation period of this virus ranges from 3-14 days or most commonly between 4-7 days.

Insect repellent containing DEET or p-menthane-3,8,-diol or menthoglycol or lemon eucalyptus oil has been found to be very effective against Aedes mosquito.

In the next article we will discuss about the treatment of Dengue Fever or Yellow Fever.

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