Anticancer Drugs Olaparib Oncology Pharmacology Physiotherapy

Olaparib (Drug Interaction-3)

In this article, we will discuss Olaparib (Drug Interaction-3). So, let’s get started.

Drugs That May Increase Olaparib Plasma Concentrations
Olaparib is primarily metabolized by CYP3A. In patients (n=57), co-administration of itraconazole, a strong CYP3A inhibitor, increased AUC of olaparib by 170%. A moderate CYP3A inhibitor, fluconazole, is predicted to increase the AUC of olaparib by 121%.

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