Alitretinoin Anticancer Drugs Oncology Pharmacology Physiotherapy

Alitretinoin (Clinical Studies-2)

In this article we will discuss Alitretinoin (Clinical Studies-2)

In this article, we will discuss Alitretinoin (Clinical Studies-2). So, let’s get started.

Alitretinoin gel was evaluated in two multicenter, prospective, randomized, double-blind, vehicle-controlled studies in patients with cutaneous lesions of AIDS-related KS. In both studies the primary efficacy endpoint was the patients’ cutaneous KS tumor response rate through 12 weeks of study drug treatment which was assessed by evaluating from 3 to 8 KS index lesions according to the modified AIDS Clinical Trials Group (ACTG) response criteria as applied to topical therapy (i.e., evaluation of height and area reductions of the index lesions only; progressive disease in non-index lesions and new lesions were not considered progressive disease; progressive disease was scored only in
the treated index lesions).

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