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Anticancer Drugs Mesna Oncology Pharmacology Physiotherapy

Mesna (Absorption)

In this article we will discuss Mesna (Absorption)

In this article, we will discuss Mesna (Absorption). So, let’s get started.

Absorption

Following oral administration, peak plasma concentrations were reached within 1.5 to 4 hours and 3 to 7 hours for free mesna and total mesna (mesna plus dimesna and mixed disulfides), respectively. Oral bioavailability
averaged 58% (range 45 to 71%) for free mesna and 89% (range 74 to 104%) for total mesna based on plasma AUC data from 8 healthy volunteers who received 1200 mg oral or intravenous doses.

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