In this article, we will discuss Sulindac and Acute Gouty Arthritis. So, let’s get started.
Acute gouty arthritis
In patients with acute gouty arthritis, the anti-inflammatory and analgesic activity of Sulindac was demonstrated by clinical measurements that included: assessments by both the patient and investigator
of overall response; relief of weight-bearing pain; relief of pain at rest and on active and passive motion; decrease in tenderness; reduction in warmth and swelling; increase in range of motion; and improvement
in ability to function. In clinical studies, Sulindac at 400 mg daily and phenylbutazone at 600 mg daily
were shown to be equally effective. In these short-term studies in which reduction of dosage was permitted according to response, both drugs were equally well tolerated.