In this article, we will discuss Palonosetron and Oral Aprepitant. So, let’s get started.
Palonosetron and Oral Aprepitant
In an interaction study in healthy subjects where a single 0.25 mg intravenous dose of
palonosetron HCl was administered on day 1 and oral aprepitant for 3 days (125 mg/80
mg/80 mg), the pharmacokinetics of palonosetron were not significantly altered (AUC: no change, Cmax: 15% increase).