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Disease Modifying Anti-rheumatic Drugs,DMARDs Mycophenolate Pharmacology Physiotherapy

Mycophenolate and Antacids

In this article we will discuss Mycophenolate and Antacids

In this article, we will discuss Mycophenolate and Antacids. So, let’s get started.

Mycophenolate and Antacids With Magnesium and Aluminum Hydroxides

Absorption of a single dose of mycophenolate mofetil (2 g) was decreased when administered to ten rheumatoid arthritis patients also taking Maalox® TC (10 mL qid). The Cmax and AUC(0-24h) for MPA were 33% and 17% lower, respectively, than when mycophenolate mofetil was administered alone under fasting conditions.

Mycophenolate may be administered to patients who are also taking antacids containing magnesium and aluminum hydroxides; however, it is recommended that Mycophenolate and the antacid not be administered simultaneously.

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