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Anticancer Drugs CAMPTOSAR Oncology Pharmacology Physiotherapy

CAMPTOSAR

In this article we will discuss CAMPTOSAR (Dosage Overview)

In this article, we will discuss CAMPTOSAR (Dosage Overview). So, let’s get started.

CAMPTOSAR is a topoisomerase inhibitor indicated for:
• First-line therapy in combination with 5-fluorouracil and leucovorin for patients with metastatic carcinoma of the colon or rectum.
• Patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following initial fluorouracil-based therapy.

Dosage

Colorectal cancer combination regimen 1: CAMPTOSAR 125 mg/m²
intravenous infusion over 90 minutes on days 1, 8,15, 22 with LV 20 mg/m² intravenous bolus infusion on days 1, 8, 15, 22 followed by 5-FU intravenous bolus infusion on days 1, 8, 15, 22 every 6 weeks.
Colorectal cancer combination regimen 2: CAMPTOSAR 180 mg/m²
intravenous infusion over 90 minutes on days 1, 15, 29 with LV 200 mg/m² intravenous infusion over 2 hours on days 1, 2, 15, 16, 29, 30 followed by 5-FU 400 mg/m2 intravenous bolus infusion on days 1, 2, 15, 16, 29, 30 and 5-FU 600 mg/m² intravenous infusion over 22 hours on days 1, 2, 15, 16, 29, 30.
Colorectal cancer single agent regimen 1: CAMPTOSAR 125 mg/m² intravenous infusion over 90 minutes on days 1, 8, 15, 22 then 2-week rest.
Colorectal cancer single agent regimen 2: CAMPTOSAR 350 mg/m² intravenous infusion over 90 minutes on day 1 every 3 weeks.

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