In this article, we will discuss Sotorasib and Carcinogenesis. So, let’s get started.
- Carcinogenicity studies have not been performed with sotorasib.
- Sotorasib was not mutagenic in an in vitro bacterial reverse mutation (Ames) assay and was not genotoxic in the in vivo rat micronucleus and comet assays.
- Fertility/early embryonic development studies were not conducted with sotorasib. There were no adverse effects on female or male reproductive organs in general toxicology studies conducted in dogs and rats.