Anticancer Drugs Oncology Pharmacology Physiotherapy

Trametinib and Hyperglycemia

In this article we will discuss Trametinib and Hyperglycemia

In this article, we will discuss Trametinib and Hyperglycemia. So, let’s get started.

Trametinib and Hyperglycemia

In the COMBI-d study, 27% of patients with a history of diabetes who received Trametinib and dabrafenib required more intensive hypoglycemic therapy. Grade 3 and Grade 4 hyperglycemia based on laboratory values
occurred in 5% and 0.5% of patients receiving Trametinib and dabrafenib, respectively. Monitor serum glucose levels upon initiation and as clinically appropriate when Trametinib is administered with dabrafenib in patients with pre-existing diabetes or hyperglycemia. Initiate or optimize anti-hyperglycemic
medications as clinically indicated.

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.