In this article, we will discuss Carmustine (Mechanism of Action). So, let’s get started.
Mechanism of Action
The mechanism of action of carmustine is not fully understood. While carmustine alkylates DNA and RNA, it is not cross-resistant with other alkylators. As with other nitrosoureas, it may also inhibit several key enzymatic processes by carbamoylation of amino acids in proteins. The metabolites may contribute to antitumor activity and toxicities of carmustine.
The exposure-response relationship for efficacy or safety is unknown.