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Anticancer Drugs Dacomitinib Medicine Oncology Pharmacology Physiotherapy

Dacomitinib

In this article, we will discuss Dacomitinib (Dosage Overview)

In this article, we will discuss Dacomitinib (Dosage Overview). So, let’s get started.

Indications

Dacomitinib is indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test.

Dosage

Patient Selection
Select patients for the first-line treatment of metastatic NSCLC with Dacomitinib based on the presence of an EGFR exon 19 deletion or exon 21 L858R substitution mutation in tumor specimens.

Recommended Dosage
The recommended dosage of Dacomitinib is 45 mg taken orally once daily, until disease progression or unacceptable toxicity occurs. Dacomitinib can be taken with or without food.
Take Dacomitinib the same time each day. If the patient vomits or misses a dose, do not take an additional dose or make up a missed dose but continue with the next scheduled dose.

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