Categories
Anticancer Drugs Medicine Oncology Pharmacology Physiotherapy Uridine Triacetate

Uridine Triacetate

In this article we will discuss Uridine Triacetate (Dosage Overview)

In this article, we will discuss Uridine Triacetate (Dosage Overview). So, let’s get started.

Indications

Uridine triacetate is indicated for the emergency treatment of adult and pediatric patients:
• following a fluorouracil or capecitabine overdose regardless of the presence of symptoms, or
• who exhibit early-onset, severe or life-threatening toxicity affecting the cardiac or central nervous system, and/or early-onset, unusually severe adverse reactions (e.g., gastrointestinal toxicity and/or neutropenia) within 96 hours following the end of fluorouracil or capecitabine administration.

Limitations of Use
• Uridine triacetate is not recommended for the non-emergent treatment of adverse reactions associated with fluorouracil or capecitabine because it may diminish the efficacy of these drugs.
• The safety and efficacy of Uridine triacetate initiated more than 96 hours following the end of fluorouracil or capecitabine administration have not been established.

Dosage

Recommended Dosage
• Adults: 10 grams (1 packet) orally every 6 hours for 20 doses, without regard to meals.
• Pediatric: 6.2 grams/m² of body surface area (not to exceed 10 grams per dose) orally every 6 hours for 20 doses, without regard to meals.

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.