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Anticancer Drugs Binimetinib Medicine Oncology Pharmacology Physiotherapy

Binimetinib

In this article, we will discuss Binimetinib (Dosage Overview)

In this article, we will discuss Binimetinib (Dosage Overview). So, let’s get started.

Indications

Binimetinib is indicated, in combination with encorafenib, for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test.

Dosage

Patient Selection
Confirm the presence of a BRAF V600E or V600K mutation in tumor specimens prior to initiating binimetinib.

Recommended Dosage
The recommended dosage of binimetinib is 45 mg orally taken twice daily, approximately 12 hours apart, in combination with encorafenib until disease progression or unacceptable toxicity. Do not take a missed dose of binimetinib within 6 hours of the next dose of binimetinib. Do not take an additional dose if vomiting occurs after binimetinib administration but continue with the next scheduled dose.

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