Vismodegib (Mechanism of Action)

In this article, we will discuss Vismodegib (Mechanism of Action). So, let’s get started.

Mechanism of Action
Vismodegib is an inhibitor of the Hedgehog pathway. Vismodegib binds to and inhibits
Smoothened, a transmembrane protein involved in Hedgehog signal transduction.

Pharmacodynamics
Cardiac Electrophysiology
The QTc interval was not affected by therapeutic doses of ERIVEDGE in a thorough QTc trial.

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