In this article, we will discuss Vismodegib (Mechanism of Action). So, let’s get started.
Mechanism of Action
Vismodegib is an inhibitor of the Hedgehog pathway. Vismodegib binds to and inhibits
Smoothened, a transmembrane protein involved in Hedgehog signal transduction.
Pharmacodynamics
Cardiac Electrophysiology
The QTc interval was not affected by therapeutic doses of ERIVEDGE in a thorough QTc trial.