Apalutamide

In this article, we will discuss Apalutamide (Dosage Overview). So, let’s get started.

Indications

Apalutamide is indicated for the treatment of patients with non-metastatic, castration-resistant prostate cancer (NM-CRPC).

Dosage

Recommended Dosage
The recommended dose of Apalutamide is 240 mg (four 60 mg tablets) administered orally once daily. Swallow the tablets whole. Apalutamide can be taken with or without food. Patients should also receive a gonadotropin-releasing hormone (GnRH) analog concurrently or should have had a bilateral orchiectomy.

Dose Modification
If a patient experiences a greater than or equal to Grade 3 toxicity or an intolerable side effect, hold dosing until symptoms improve to less than or equal to Grade 1 or original grade, then resume at the same dose or a reduced dose (180 mg or 120 mg), if warranted.

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