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Anticancer Drugs Cabazitaxel Medicine Oncology Pharmacology Physiotherapy

Cabazitaxel

In this article we will discuss Cabazitaxel (Dosage Overview)

In this article, we will discuss Cabazitaxel (Dosage Overview). So, let’s get started.

Indications

Cabazitaxel is a microtubule inhibitor indicated in combination with prednisone for the treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.

Dosage

General Dosing Information

• The individual dosage of Cabazitaxel is based on calculation of the Body Surface Area (BSA) and is 25 mg/m² administered as a one-hour intravenous infusion every three weeks in combination with oral prednisone 10 mg administered daily throughout Cabazitaxel treatment.
• Premedication is recommended prior to treatment.
• Cabazitaxel should be administered under the supervision of a qualified physician experienced in the use of antineoplastic medicinal products. Appropriate management of complications is possible only when the adequate diagnostic and treatment facilities are readily available.
• Cabazitaxel Injection single-use vial requires two dilutions prior to administration.
• Do not use PVC infusion containers and polyurethane infusions sets for preparation and administration of Cabazitaxel infusion solution.
• Both the Cabazitaxel Injection and the diluent vials contain an overfill to compensate for liquid loss during preparation.

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