In this article, we will discuss Lincosamides (Dosage). So, let’s get started.
Lincosamides
Clindamycin hydrochloride 20-30 mg/kg/day q 6-8 hr oral, 20-40 mg/kg/day q 6-8 hr IV. Dilute for slow infusion over 30 min. Useful for MRSA, anerobic infections, P.carinii, pneumonia and toxoplasma encephalitis.
Adult doses: 150-450 mg q 6-8 hr.
Caution: Pseudomembranous colitis. Avoid coadministration with erythromycin.
(Dalcinex, dalacin-c, clincin caps 150 mg, 300 mg; inj dalacin, climycin 150 mg per ml in 2 ml, 4 ml ampoules, erytop, cleargel and clindapene (1%) gel for acne).
Lincomycin 30-60 mg/kg/day q 8 hr oral. 10-20 mg/kg/day q 8-12 hr IM, IV.
Adult dose: 250-500 mg q 8 hr oral; 600 mg single dose IM, 600 mg q 8-12 hr IV.
Caution: Pseudomembranous colitis, TEN syndrome, DRESS (Drus Reaction with Eosinophilia and Systemic symptoms) syndrome.
(Lynx, lincosa, lincosin, lysin caps 250 mg, 500 mg; syrup 125 mg per ml; inj 300 mg per ml, 1 ml, 2 ml amp).