Differential Diagnosis and Complications of Acute Pancreatitis

In this article, we will discuss the Differential Diagnosis and Complications of Acute Pancreatitis. So, let’s get started.

Differential Diagnosis

Differential diagnosis includes the following conditions i.e.

  • Perforated peptic ulcer
  • Acute cholecystitis and biliary colic
  • Acute intestinal obstruction
  • Inferior myocardial infarction
  • Mesentery vascular occlusion
  • Dissecting aortic aneurysm
  • Diabetic ketoacidosis
  • Vasculitis


They are both local and systemic:

1. Local

  • Pancreatic necrosis
  • Pancreatic fluid collection, e.g. abscess, pseudocyst
  • Pancreatic ascites
  • Involvement of adjoining organs and vessels
  • Obstructive jaundice

2. Systemic

  • Pulmonary, e.g. pleural effusion, pneumonitis, ARDS, atelectasis and mediastinal abscess
  • Renal, e.g. oliguria, azotemia, ATN (acute tubular necrosis) and renal artery/venous thrombosis
  • Cardiovascular, e.g. hypotension, pericardial effusion and sudden death
  • Hematological, e.g. disseminated intravascular coagulation
  • GI hemorrhage, e.g. peptic ulcer disease, hemorrhagic pancreatic necrosis, portal vein thrombosis
  • Metabolic, e.g. hyperglycemia, hypertriglyceridemia, hypocalcemia and encephalopathy
  • CNS, e.g. psychosis, fat emboli.

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