Causes of Acute Respiratory Distress Syndrome

In this article, we will discuss various Causes of Acute Respiratory Distress Syndrome. So, let’s get started.


Systemic insults (indirect injury)

  • Trauma, head injury
  • Shock, sepsis
  • Pancreatitis
  • Repeated blood transfusion
  • Disseminated intravascular coagulation (DIC)
  • Burns
  • Drugs, e.g. opiates, aspirin, phenothiazines, tricyclic antidepressants, nitrofurantoin, amiodarone, paraquat
  • Thrombotic Thrombocytopenic Purpura
  • Cardiopulmonary bypass

Pulmonary insults (direct injury)

  • Aspirations of gastric contents
  • Embolism, e.g. thrombus, fat, air, and amniotic fluid
  • Miliary tuberculosis
  • Diffuse pneumonia, acute eosinophilic pneumonia, cryptogenic pneumonia
  • Near drowning
  • Toxic gas inhalation, e.g. CO, NO2, PH3, chlorine, SO2, ammonia, hyperbaric O2
  • Lung contusion
  • Radiation exposure
  • High altitude pulmonary edema
  • Lung re-expansion or re-perfusion

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