Causes of Left Ventricular Failure

In this article, we will discuss various Causes of Left Ventricular Failure. So, let’s get started.


1. Left Ventricular Outflow Obstruction (pressure overload)

  • Systemic hypertension
  • Aortic valvular stenosis (congenital or acquired)
  • Hypertrophic cardiomyopathy

2. Left Ventricular Inflow Obstruction

  • Mitral stenosis
  • Left atrial myxoma
  • Endomyocardial fibrosis (left ventricle)

3. Left Ventricular Volume Overload

  • Mitral regurgitation or mitral valve prolapse
  • Aortic regurgitation (rheumatic and non-rheumatic)
  • Ventricular Septal Defect
  • Patent ductus arteriosus
  • High output states (anemia, thyrotoxicosis, beri beri, AV fistula, Paget’s disease)
  • Papillary muscle dysfunction

4. Reduced left ventricular contractility

  • Dilated cardiomyopathy (LV predominant)
  • Anterior wall MI
  • Myocarditis and left ventricle endocarditis

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