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Medicine Physiotherapy Pituitary Apoplexy

Clinical Presentations of Pituitary Apoplexy

In this article we will discuss the Clinical Presentations of Pituitary Apoplexy

In this article, we will discuss the Clinical Presentations of Pituitary Apoplexy. So, let’s get started.

Signs and Symptoms

  • Headache, sudden and severe retro-orbital and frontal pain
  • Decreased visual acquity and visual field defects
  • Opthalmoplegia, ptosis, and pupilary defects
  • Nausea, vomiting, headache, alteration in the level of consciousness, e.g. lethargy, stupor, and coma
  • Hemiplegia
  • Acute adrenal insufficiency
  • Gonadal dysfunction
  • Diabetes insipidus
  • Hypofunction of thyroid
  • Fever, anosmia, CSF rhinorrhea, and facial pain, respiratory and cardiac rhythm disturbances

Structure involved/compressed

  • Sudden enlargement of tumor mass
  • Optic nerve
  • The III,IV, and VI cranial nerve compression
  • Meningeal irritation (disruption of dura or leakage of blood into subarachnoid space)
  • Internal carotid artery
  • Compression of corticotrophs (loss of ACTH)
  • Compression of gonadotrophs (loss of LH, FSH)
  • Compression of pituitary stalk
  • Compression of thyrotrophs
  • Nonspecific, noncompressive

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