Categories
Oncology Physiotherapy

Study Reveals Gaps in Oncology Guideline Adherence Across Tertiary Cancer Centers

Study Reveals Gaps in Oncology Guideline Adherence Across Tertiary Cancer Centers Researchers examined adherence to oncology patient care guidelines in major tertiary cancer centers. They compared national standards from ICMR and NCI-India with international ones from ASCO, ESMO, and NCCN. The analysis focused on how closely doctors followed these guidelines. It also measured links to […]

Categories
Physiotherapy

Diagnostic delays in oral cancer among tobacco users in India: Analysis of referral pathways and stage at presentation

Oral cancer remains a major health concern in India. Tobacco use drives a large share of cases. Many patients reach hospitals only after the disease has advanced. Diagnostic delays play a critical role in this pattern. Patients often wait long before seeking care. They also face further delays after contacting the health system. As a […]

Categories
Physiotherapy

The Placebo-Nocebo Paradox: Mind Over Matter

The Placebo-Nocebo Paradox: Mind Over Matter The Placebo-Nocebo Paradox highlights the power of expectations in shaping reality. Positive expectations can heal, while negative expectations can harm. Key Points: Placebo Effect: Inert substances or treatments produce real benefits due to positive expectations. Nocebo Effect: Negative expectations lead to adverse outcomes. Implications: Mind-Body Connection: Expectations influence physical […]

Categories
Physiotherapy

Oxaliplatin: A Closer Look at Its Mechanism of Action

Oxaliplatin is a platinum-based chemotherapy drug used to treat various cancers. Its mechanism of action involves several key steps: Activation: Oxaliplatin is a prodrug, meaning it needs to be activated to exert its cytotoxic effects. Once administered, it undergoes a series of chemical reactions that lead to the formation of active platinum species. DNA Binding: […]

Categories
Anticancer Drugs Oncology Pharmacology Physiotherapy

Bortezomib: A Proteasome Inhibitor

Bortezomib, sold under the brand name Velcade among others, is a medication used to treat multiple myeloma and mantle cell lymphoma. It is a proteasome inhibitor, which means it blocks the activity of a protein called the proteasome. The proteasome is responsible for breaking down proteins in cells, including cancer cells.    Bortezomib is a […]

Categories
Anticancer Drugs Oncology Pharmacology Physiotherapy

Vinorelbine

Vinorelbine is a chemotherapy medication that is sometimes used to treat non-small cell lung cancer (NSCLC). It is often used in combination with other chemotherapy drugs, such as cisplatin or pemetrexed. Vinorelbine works by interfering with the growth and division of cancer cells. When used to treat NSCLC, vinorelbine can help to shrink tumors and […]