Multi-omics Integration for Individualized Treatments revolutionizes medicine today. Doctors no longer rely on one-size-fits-all approaches. They combine multiple data layers instead. Multi-omics studies several biological levels at once. Genomics reveals DNA variations. Transcriptomics shows gene expression. Proteomics measures proteins. Metabolomics tracks small molecules. Epigenomics examines chemical tags on DNA. Researchers integrate these layers. This creates […]
Author: priyeshbanerjeept
Physiotherapist, Certified MFR therapist on a mission to provide one stop search destination for various diseases its symptoms,causes,diagnosis,treatment, physiotherapy management,rehabilitation with practical examples for aspiring physiotherapists,medical professionals and general public.
Suzetrigine, branded as Journavx, marks a major breakthrough. Vertex Pharmaceuticals developed this innovative drug. The FDA approved it on January 30, 2025. It becomes the first new class of pain medicine in over 20 years. Journavx targets moderate-to-severe acute pain in adults. It offers a non-opioid oral option. Moreover, it avoids addictive potential completely. Patients […]
Organ-on-Chip and In-Silico Trials Revolutionize Drug Testing Organ-on-chip technology mimics human organs. Microfluidic devices house living cells. These chips recreate organ functions accurately. Blood flow circulates through tiny channels. Mechanical forces simulate breathing or heartbeat. Researchers grow cells on flexible membranes. They form tissues that behave like real organs. Lung-on-chip shows gas exchange. Liver-on-chip processes […]
Alkali Denaturation Test for HbF Explained Simply Doctors use this test to measure fetal hemoglobin. It works well in newborns and thalassemia cases. Therefore, labs rely on it often. The test exploits a key difference. Adult hemoglobin (HbA) denatures quickly in strong alkali. Fetal hemoglobin (HbF) resists denaturation strongly. As a result, HbF stays soluble […]
Finkelstein Test Demonstration Steps Doctors use this test to detect De Quervain’s tenosynovitis. It stretches the thumb tendons sharply. Pain on the thumb side of the wrist indicates a positive result. Use this modern 3-step version. It starts gently. Then it increases the stretch. Finally, it performs the classic move. Step 1: Gravity-Assisted Ulnar Deviation […]
Exon-Skipping ASOs for SMA: Nusinersen Leads the Way in 2026 Spinal muscular atrophy weakens muscles severely. It affects motor neurons early in life. SMN1 gene mutations cause the disease. SMN2 gene partially compensates. However, SMN2 skips exon 7 in most transcripts. This produces unstable protein. Therefore, functional SMN levels stay low. Antisense oligonucleotides (ASOs) change […]