Categories
Antiviral Agents Pharmacology Physiotherapy

Acyclovir (Zovirax)

In this article we will discuss Acyclovir (Zovirax)

In this article, we will discuss Acyclovir (Zovirax). So, let’s get started.

Acyclovir

Acyclovir Neonatal HSV: Skin, eye and mouth disease: 20 mg/kg q 8 hr IV for 14 days; Disseminated and CNS disease: 20 mg/kg q 8 hr IV for 21 days. HSV encephalitis: Age >28 days to <12 yrs: 20 mg/kg q 8 hr IV for 21 days; ≥12 yrs: 10 mg/kg q 8 hr IV for 21 days. Varicella in immunocompetent host: 20 mg/kg q 6 hr (maximum 800 mg/dose) for 5 days (beneficial only when given within first 24 hours of onset of rash). Recommended only in individuals at increased risk of moderate to severe varicella: Non-pregnant individuals >12 yr, individuals >12 months with chronic cutaneous and pulmonary disorder, short-term steroid, long-term salicylate therapy and secondary cases of household contacts. Varicella-zoster in immunocompromised children: 10 mg/kg q 8 hr or 500 mg/m²/dose q 8 hr for 7-10 days. Herpes zoster or chickenpox in adolescents and adults 800 mg q 6 hr for 5 days. Herpes simplex 200 mg q 4 hr for 5 days.

Caution: The recommended final concentration for IV administration is ≤7 mg/ml. Administer over at least one hour to prevent renal tubular damage.

(Zovirax, acivir, ocuvir, axovir, acyclor, herperex, herpikind, herpex tabs 200 mg, 400 mg, 800 mg; zovirax susp 400 mg/5 ml in 100 ml bottle, inj acivir, zovirax 250 mg 1 ml ampoule; ophthalmic ointment 3% and herpex, ocuvir skin ointment 5%).

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.