Classification of Guillain-Barré Syndrome

In this article, we will discuss the Classification of Guillain-Barré Syndrome. So, let’s get started.

Classification

Subtype

1. Acute inflammatory demyelinating polyradiculopathy (AIDP)

Characteristics

  • Demyelinating
  • Adults affected more than children
  • Anti-GM antibodies present (>50%)
  • Recovery rapid

Subtype

2. Acute motor axonal neuropathy (AMAN)

Characteristics

  • Axonal damageChildren and young adults affected
  • Prevalent in China and Mexico
  • Anti-GD1a antibodies present
  • Recovery rapid

Subtype

3. Acute motor-sensory axonal neuropathy (AMSAN)

Characteristics

  • Axonal damage
  • Uncommon, adults affected
  • Closely related to AMAN
  • Recovery slow

Subtype

4. Miller-Fisher Syndrome

Characteristics

  • Demyelinating, uncommon
  • Affects children and adults
  • Ophthalmoplegia, ataxia and areflexia occur
  • Anti GQ-1b antibodies present (>90%)
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