Clinical Features of Barbiturates Poisoning

In this article, we will discuss the Clinical Features of Barbiturates Poisoning. So, let’s get started.

Clinical Features

The clinical features are mainly due to CNS depression followed by features of respiratory depression and hypotension.

  • CNS depression: Confusion, lethargy, depressed mental activity, decreased responsiveness to external stimuli, dilated pupils, depressed tendon reflexes and extensor plantar response are seen.
  • Respiratory depression: It causes Cheyne-stoke’s respiration, apnea, aspiration pneumonia and respiratory acidosis
  • Other features include hypotension, shock, hypothermia, acute renal failure and a characteristic bullous rash seen on pressure points like elbow or malleolus after 2-3 days
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