Drugs causing Thrombocytopenia

In this article, we will discuss various Drugs responsible for causing Thrombocytopenia. So, let’s get started.

List of Drugs

I. Drugs that suppress platelet production

  • Myelosuppressive drugs, e.g. cytosine, arabinoside, daunorubicin, cyclophosphamide, busulfan, methotrexate, 6-mercaptopurine, vinca alkaloids
  • Thiazide diuretics
  • Ethanol
  • Estrogen

II. Immunologic platelet destruction

  • Antibiotics, e.g. sulphonamide, tetracyclines, novobiocin, PAS, rifampicin, chloramphenicol,
  • Cinchona alkaloids, e.g. quinine, quinidine
  • Sedatives, hypnotics, anticonvulsants (carbamazepine)
  • Digoxin
  • Alpha methyldopa
  • Anti-inflammatory, e.g. aspirin, phenylbutazone
  • Chloroquine, gold salts, arsenicals
  • Insecticides
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