Signs and Symptoms of Adrenal Insufficiency

In this article, we will discuss various Signs and Symptoms of Adrenal Insufficiency. So, let’s get started.

Signs and Symptoms

Glucocorticoid deficiency

  • Weight loss, weakness, lack of energy, fatigue
  • Anorexia, nausea, vomiting
  • Diarrhea or constipation
  • Postural hypotension, syncope, shock
  • Joint pain, myalgia
  • Hypoglycemia, hyponatremia, and hypercalcemia
  • Anemia, lymphocytosis, eosinophilia

Mineralocorticoid insufficiency

  • Postural hypotension
  • Shock
  • Hyponatremia
  • Salt craving and abdominal pain
  • Hyperkalemia

ACTH excess

  • Pigmentation on sun-exposed areas, pressure sores, e.g. elbow, knee and mucous membrane, conjunctivae, palmar creases, and recent scars

Adrenal androgen insufficiency

  • Decreased body hair (e.g. pubic, axillary) and loss of libido especially in females
  • Lack of energy
  • Dry and itchy skin

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