Category: Medicine

Sodium Channel Blockers for Pain: Nav1.7 Inhibitors Explained Pain signals travel through nerves.These signals depend on sodium channels.One key channel is called Nav1.7. Nav1.7 is found in peripheral sensory nerves.It plays a major role in pain transmission.When Nav1.7 is overactive, pain increases. Scientists discovered something important.People born without Nav1.7 function feel no pain.They can sense […]

Enterovirus D68 Outbreaks and Respiratory Disease Enterovirus D68 is a non-polio enterovirus.It primarily affects the respiratory system.The virus spreads through respiratory droplets. Most infections occur in children.However, adults can also be affected.Severe illness is more common in children with asthma. Outbreaks are often seasonal.They usually peak in late summer and autumn.Schools and childcare settings aid […]

Crisugabalin: A New Direction in Pain Treatment Crisugabalin is an investigational pain-relief drug.It belongs to the gabapentinoid class.It is related to pregabalin and gabapentin. But it is not the same.Crisugabalin was designed to act more selectively.The goal is better pain control with fewer side effects. What Is Crisugabalin Crisugabalin is also known as Mirogabalin-like gabapentinoid […]

Phase I dose-escalation studies are the first step in human trials.They usually involve a small number of participants.Most are conducted in patients, especially in cancer research. The main goal is safety.Researchers aim to find a safe dose range.Efficacy is not the primary focus. Dose escalation is done gradually.Patients receive increasing doses in cohorts.Careful monitoring follows […]

Advanced Life Support in Critical Care Units Advanced life support plays a central role in modern hospitals.In particular, it is delivered inside critical care units.These specialized units manage patients with life-threatening conditions. Rather than offering basic assistance, advanced life support goes much further.As a result, it helps sustain organs that are failing.At the same time, […]

Fever-reducing drugs are commonly used across age groups.However, renal safety remains a key medical concern. The kidneys play a vital role in filtering blood.At the same time, they regulate fluid and electrolyte balance. Certain antipyretic medicines can affect kidney function.Therefore, correct dosing becomes essential. Paracetamol is generally considered kidney safe.Nevertheless, misuse or overdose can still […]