In this article, we will discuss the Laboratory parameters in hyperosmolar hyperglycemic non-ketotic coma. So, let’s get started.
Laboratory parameters
- Plasma glucose (mg/dl)= >600 (600-1200 mg/dl)
- Arterial pH= osmolality >7.30
- Serum bicarbonate (mEq/L)= >15 mEq/L
- Effective serum osmolality (mOsm/kg)= >350 (350-800 mOsm/kg)
Note: The effective serum osmolality is calculated by= 2x Na(mEq/L)+ glucose divided by 18 (mg/dl)+ BUN/2.8
- Anion gap [(Na+) + (K+)] – [(Cl-) – (HCO3-)]= 20
- Urine or serum ketone= Small or absent
- Blood urea/creatinine= May be high (pre renal azotemia)
- Serum sodium (mEq/L)= 135-145 mEq/L