Predisposing Factors for Anaphylaxis

In this article, we will discuss various Predisposing Factors for Anaphylaxis. So, let’s get started.

Predisposing Factors

1. Drugs

  • Penicillin, cephalosporins, amphotericin B
  • Local anaesthetics, e.g. procaine, lidocaine
  • Vitamins, e.g. thiamine, folic acid
  • Contrast medium agents
  • Occupational related agent, e.g. ethylene oxide
  • Antisera, dextran, albumin
  • Cyclosporine
  • Opiates
  • NSAIDs and azo-dyes

2. Hymenopetra venoms

  • Hornets, wasp, honeybee, ants

3. Heterologous Proteins

  • Hormones, e.g. insulin, vasopressin, paratharmone
  • Enzymes, e.g. trypsin, chymotrypsin, penicillinase

4. Foods

  • Eggs, sea food, nuts, grains, beans

5. Pollen extracts

  • Ragweed, grass, trees

6. Nonpollen extracts

  • Dust mites, cot dander

7. Idiopathic

  • Blood transfusion (immune complex mediated), e.g. whole blood, plasma, and immunoglobulins

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