Clinical Criteria for Severity of Acute Pancreatitis

In this article, we will discuss the Clinical Criteria for Severity of Acute Pancreatitis. So, let’s get started.

Ranson’s criteria

1. At admission (three or more indicate severe disease)

• Age >55 years
• TLC >16000/mm3
• Blood sugar >220 mg/dL
• LDH >350 IU/L
• Aspartate amino transferase 7250 units
• Base deficit >4 mEq/L
• Fluid sequestration >6 L

Glasgow criteria

1. At admission (three or more indicate severe disease)

• Age >55 years
• PaO2 <8 kPa
• WBC > 15×10⁹L
• Albumin <32 g/L (3.2 g%)
• Serum calcium <2 mmol/L

Ranson’s criteria

2. Initial 48 hours (development of the following indicates worse prognosis)

• Hematocrit decrease by >10%
• BUN increase by > 5 mg/dL
• Serum calcium <8 mg/dL
• PaO2 <60 mmHg
• Base deficit >5 mEq/L

Glasgow criteria

2. Initial 48 hours (development of the following indicates worse prognosis)

• Glucose >10 mmol/L
• Urea >16 mmol/L (after rehydration)
• ALT >200 U/L
• LDH >800 U/L