Clinical Features and Pathophysiology of Myofascial Pain Syndrome

In this article, we will discuss the Clinical Features and Pathophysiology of Myofascial Pain Syndrome. So, let’s get started.

Myofascial Pain Syndrome is characterized by:

Trigger points (usually in mid-portion or belly of the affected muscle)

A Taut band (<1 cm2)

Local twitch response followed by “Snapping Palpation”

Clinical Features

Regional pain

Referred pain

Disturbed sensation in a predicted location

Taut band

Tender point

Restricted range of motion

Weather sensitivity

Sleep disturbance


Pathophysiology (>> means next step)

Acute muscle strain>> Tissue damage>> Tears in Sarcoplasmic Reticulum>> Free Ca++>> Sustained contraction>> Increased strain on vulnerable areas>> Free Ca++>> Local hypermetabolic state and vasoconstriction.


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