In this article, we will discuss about the diagnosis of dermatomyositis. So, let’s get started.
Shawl’s sign, V-sign, and holster sign
Skin biopsy demonstrates reduced capillary density, deposits of membrane attack complex within the walls of dermal blood vessels and on small blood vessels along the dermal-epidermal junction.
Elevated serum level of CK, aldolase, LDH, and ALT/SGPT, and AST/SGOT
Symmetrical muscle weakness in upper and lower extremity
EMG reveals short, small, low-amplitude polyphasic motor unit potentials, fibrillation potentials, and high-frequency repetitive discharges
Elevated ESR and CRP levels
Muscle biopsy finding reveals perivascular inflammation, perifascicular atrophy, active phagocytosis, active regeneration, interstitial mononuclear infiltrate, central nuclei, and vasculitis
Nondestructive arthritis or arthralgias, and myalgias