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Diagnosis of dermatomyositis

In this article, we will discuss about the diagnosis of dermatomyositis. So, let’s get started.

Diagnosis

Heliotrope rash

Gottron’s sign

Shawl’s sign, V-sign, and holster sign

Periungual telangiectasias

Skin biopsy demonstrates reduced capillary density, deposits of membrane attack complex within the walls of dermal blood vessels and on small blood vessels along the dermal-epidermal junction.

Elevated serum level of CK, aldolase, LDH, and ALT/SGPT, and AST/SGOT

Symmetrical muscle weakness in upper and lower extremity

EMG reveals short, small, low-amplitude polyphasic motor unit potentials, fibrillation potentials, and high-frequency repetitive discharges

Fever

Elevated ESR and CRP levels

Muscle biopsy finding reveals perivascular inflammation, perifascicular atrophy, active phagocytosis, active regeneration, interstitial mononuclear infiltrate, central nuclei, and vasculitis

Nondestructive arthritis or arthralgias, and myalgias

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