Causes of hemolytic anemia

In this article, we will discuss about the various causes of hemolytic anemia. So, let’s get started.


Inherited diseases such as thalassemia, sickle cell anemia, G6PD deficiency, hereditary spherocytosis and elliptocytosis, congenital dyserythropoietic anemia, pyruvate kinase deficiency, and paroxysmal nocturnal hemoglobinuria.

Autoimmune causes such as SLE, scleroderma, Hodgkin’s disease, ulcerative colitis, chronic lymphocytic leukemia, rheumatoid arthritis.


Infections such as mycoplasma pneumonia, malaria, etc.

Certain drugs such as cephalosporin, dapsone, levodopa, levofloxacin, snake or spider venom or lead, arsine or stibine poisoning.

Enlarged or hyperfunctioning spleen

Advanced liver or kidney disease.

Prosthetic heart valve, vascular grafts recipients, cancer, exposure to certain chemicals or clotting disorders.

Footstrike hemolysis in runners.

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