In this article we will discuss about What is Hypertrichosis? So let’s get started.
It is also known as “Werewolf syndrome” characterized by abnormal hair growth all across the body. It is an extremely rare disease. It is of following types:
Congenital Hypertrichosis lanuginosa
Congenital Generalized Hypertrichosis
Congenital Localised Hypertrichosis
Congenital Hypertrichosis Terminalis
Congenital Circumscribed Hypertrichosis
Congenital Nevoid Hypertrichosis
Acquired Hypertrichosis lanuginosa
Acquired Generalized Hypertrichosis
Acquired Localised Hypertrichosis
Acquired Patterened Hypertrichosis
Congenital Hypertrichosis lanuginosa is caused due to paracentric inversion mutation of q22 band of chromosome 8. It is of autosomal dominant form.
Congenital Generalized Hypertrichosis is linked to chromosome Xq24-27.1.
Congenital Hypertrichosis Terminalis is caused due to mutaion in chromosome 17. It is also associated with mutation in gene MAP2K6.
Medications like cyclosporine, phenytoin, psoralen, minoxidil, diazoxide, acetazolamide, streptomycin are responsible to cause Hypertrichosis.
Symptoms include excessive hair growth in generalized it is present all over the body, in localised and circumscribed it is present in specific and restricted area. In Patterened hair growth occurs in a distinct pattern and based on hair type it can be lanugo, vellus or terminal.